Deapio-platycodin D - Names and Identifiers
Name | Deapio-platycodin D
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Synonyms | Deapioplatycodin D Deapi-platycodin D Deapio-platycodin D Desapioplatycodin D Deapio-platycodin-D,Deapi-platycodin D,Deapioplatycodin D,Desapioplatycodin D Olean-12-en-28-oic acid, 3-(β-D-glucopyranosyloxy)-2,16,23,24-tetrahydroxy-, O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,16α)- (2beta,3beta,16alpha)-3-(beta-D-glucopyranosyloxy)-2,16,23,24-tetrahydroxyolean-12-en-28-oic acid O-beta-D-xylopyranosyl-(1-4)-O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-alpha-L-arabinopyranosyl ester
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CAS | 78763-58-3
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Deapio-platycodin D - Physico-chemical Properties
Molecular Formula | C52H84O24
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Molar Mass | 1093.22 |
Density | 1.53 |
Melting Point | 231-235°C |
Specific Rotation(α) | (c, 1 in MeOH)-22.9 |
Solubility | Easily soluble in water and methanol, insoluble in petroleum ether and chloroform. |
Appearance | White powder |
pKa | 12.76±0.70(Predicted) |
Storage Condition | 2-8℃ |
Sensitive | Easily absorbing moisture |
MDL | MFCD21364037 |
Deapio-platycodin D - Reference
Reference Show more | 1. Zhang Ling, Guo Xuanxuan, Zhu Li. Distribution and dynamic accumulation of bitter substances in Platycodon grandiflorum [J]. Chinese new drugs and clinical pharmacology, 2019, 030(005):586-591. 2. Zhang, Chi, et al. "Components study on antitussive effect and artistic mechanism of Platycodonis Radix-based on spectrum-effect relationship and metabonomics analysis." Journal of Chromatography B 1173 (2021): 122680.https://doi.org/10.1016/j.jchromb.2021 3. [IF = 4.821] Xiangwei Chang et al."Untargeted metabolomics approach reveals the tissue-specific markers of balloon flower root (Platycodi Radix) using UPLC-Q-TOF/MS."Microchem J. 2021 Sep;168:106447 4. [IF=3.935] Tong Xie et al."A post processing strategy to score and rank the annotation confidence of saponins in natural products by integrating MS2 spectral similarity and fragment interpretation."J Pharmaceut Biomed. 2021 Sep;204:114291 5. [IF=3.205] Chi Zhang et al."Components study on antitussive effect and holistic mechanism of Platycodonis Radix based on spectrum-effect relationship and metabonomics analysis."J Chromatogr B. 2021 May;1173:122680 6. [IF=3.205] Chi Zhang et al."Active microbial metabolites study on antitussive and expectorant effects and metabolic mechanisms of platycosides fraction of Platycodonis Radix."J Chromatogr B. 2022 Apr;1195:123171 |
Deapio-platycodin D - Introduction
Deapio-platycodin D, also known as apigenin D, is a natural compound derived from plants. The following is a description of the nature, use, preparation and safety information of Deapio-platycodin D:
Nature:
-The chemical structure of Deapio-platycodin D is a six-membered ring triterpene saponin with a larger molecular weight.
-This compound is a white to off-white crystalline powder at room temperature.
- Deapio-platycodin D is insoluble in water, but soluble in polar solvents such as methanol.
Use:
- Deapio-platycodin D has a variety of pharmacological activities and is a potential biologically active ingredient.
-The compound shows anti-inflammatory, anti-tumor and antioxidant activity.
-The study found that Deapio-platycodin D has inhibitory effects on some cancer cell lines and shows potential value in anti-cancer treatment.
Preparation Method:
- Deapio-platycodin D is usually obtained from plants containing the compound by plant extraction methods.
-A common method of extraction is by solvent extraction, such as methanol or alcohol-water mixtures.
Safety Information:
-The current safety research on Deapio-platycodin D is limited, so further evaluation of its safety is needed.
-When using this compound, its solubility in solvents should be considered to ensure safe use.
-If Deapio-platycodin D is to be used in medicine or other applications, it is recommended to use and optimize the dosage under the guidance of a professional.
Last Update:2024-04-09 20:49:11